Peddapalli District is carved out of erstwhile Karimnagar district. It is surrounded by Mancherial, Bhoopalapally, Karimnagar, Jagtial districts. The district comprises 14 mandals and two revenue divisions – Peddapalli and Manthani. Peddapalli town is its headquarters.

The district has some major railway lines including the one connecting the north and south India passing through it. Hyderabad-Ramagundam State Highway also crisscrosses the district. This well-connected district has three RTC depots at Godavarikhani, Ramagundam and Manthani.

NTPC Ramagundam, a part of National Thermal Power Corporation, is situated at Ramagundam. It is one of the major power stations in South India and is the first ISO 14001 certified “Super Thermal Power Station” in India. The district is also home to major industries like Singareni, FCI and many private cement factories.

River Godavari passes through Peddapalle district and the entire district is covered under SRSP command area. The district is known for its paddy to produce followed by cotton and maize. The cotton produced here is internationally reputed for its quality. It is also dotted by many rice mills and spinning mills.

The district is of historical and archaeological significance. The Buddhist Stupa dating back to 2nd century BC and one of the 30 walled cities mentioned by Megasthenes, the Greek historian, is located in Dhulikatta village of Eligaid mandal.

Peddaplli district is adorned by the holy shrines of Sri Mallikarjuna Swamy at Odela and Sri Varahaswami at Kamanpur Mandal. Some of the popular tourist attractions in the district include Ramuni Gundalu, Sabbitham waterfalls. Ramagiri Qilah, a place of historical importance located in the village Begumpet is also often visited by tourists.

Some of the tourist spots in the districts are: Ramuni Gundalu, waterfalls at Sabbitham. Ramagiri Qila is a place of historic importance and is located at Begumpet.